Whole Human Brain Slicing Machine
We have been specialising in the development and production of cryostats for over 50 years. Our 10400 Cryostat has been developed from our 9400 Cryostat and has been adapted to handle even larger specimens.
A Highly Specialised, Patent Protected Cryostat
The Bright Instruments 10400 machine has been developed from our 9400 cryostat and has been adapted to handle even larger specimens.
It is protected under Patent GB18031310.
Whole brain sectioning is a crucial step for neuroscience research, enabling the study of brain-wide structures, neural circuits, and pathology. Proper handling and sectioning are essential to preserve the intricate architecture of the brain, providing detailed maps of gene expression or cellular distribution. This is especially useful in developmental neuroscience, neurodegenerative disease studies, and functional brain mapping.
The adjustable cryostat deep-freezing temperature preserves the brain’s cellular structure and molecular integrity, making it ideal for studying specific proteins, neurotransmitters, or gene expression patterns.
The deep chamber & range of cutting allows for coronal sectioning – an important consideration for clinicians because this allow visualization of some of the brain’s most important structures.
The large cryostats are made to order and can have additional design specifications as determined by the customer application – please contact us to discuss your research needs.
Key Features
Touchscreen
The Control panel is the central point of control for the unit,allowing the user to easily customise settings such as temperature, thickness, batch quantities and switch between single and continuous cutting modes.
Please contact your specialist here to find out more to discuss bespoke solutions.
Full Details
Specification 
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Cryostat Specification: -
Refrigeration - No. of Compressors Minimum Temperature
2 (Dual Compressor) -35°C @ 21°C Ambient -
Chamber
Stainless steel -
Illumination
LED light strip x 2 -
De-misting
Automatically operated Triplex heated glass window. -
Cabinet
PVC coated sheet steel. -
Dimensions
Chamber dimensions: H1315 x W1250 x D608mm, Cabinet dimensions: H1630 x W2600 x D890mm (Excluding control unit) H2060 x W2600 x D890mm (Including control unit) -
Macrotome Specification: -
Construction
Solid aluminium frame with a powder-coated gloss finish. -
Section Thickness Range
1μm to 200μm in 1μm increments. (It is advised that a machine of this size is not used to section below 5 microns). -
Knife Block Movement
N/A. Fixed. -
Cutting Stroke
490 mm -
Maximum Specimen
Size 300 (H) x 210 (W) x 400 (L) mm -
Movement
Automatic operation, Fixed blade, horizontal and vertical axis table movement. -
Cutting speed range
0-80mm/sec -
Anti-roll system
Adjustable Perspex anti-roll plate. -
Electrical
240V AC Single Phase, Neutral, Earth. 50Hz. 20A.
Features & Benefits
- Touch screen Control.
- Waste collection tray.
- Heated anti-fog window.
- Can cut a large range of specimen sizes up to 400 x 150 x 110mm.
- Chamber can be cooled down to temperatures of -40.
- Customisable Zonal speed control for quicker sectioning.
- Solid steel/Tungsten knife & disposable blade options available.
- Knee switch (optional).
- Easy to clean.
- Ample cold storage.
- 3-5 year warranty (optional)
Downloads
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Manual
Product Video
Coming Soon…
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